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Anupurna Kaul, Ph.D.

Anupurna Kaul, Ph.D.

Postdoctoral Scholar
Transplant Immunologist
Tang and Bluestone Labs

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  • Tang Lab, Department of Surgery. 2016 -
  • Bluestone Lab, UCSF Diabetes Center, 2016 -

 Anupurna Kaul is a transplant immunologist working on CARs (Chimeric Antigen Receptors) project in the Transplantation Research laboratory of Dr. Qizhi Tang (Department of Surgery) in collaboration with the Diabetes Center.  Dr. Kaul completed her PhD under the supervision of Dr. William Baldwin at Cleveland Clinic in 2014. She worked on the emerging concept of the balance of negative and positive signals in the alloimmune response in cardiac allograft vasculopathy. Her dissertation study was designed to discover molecular mediators that differentially modulate acute mononuclear infiltrates in the myocardium and chronic infiltrates in the large arteries. She joined Dr. Tang's lab in 2016 as a Postdoc Scholar. Her work currently focuses on developing HLA-targeting chimeric antigen receptors (CARs) for Treg therapy in transplantation and optimizing the design of the intracellular domain of CAR for supporting Treg homeostasis and functions. The overall goal of this project is to induce immune tolerance to the donor graft using the CAR technology.

    1. Kaul A M, Goparaju S, Dvorina N, Iida S, Keslar KS, de la Motte CA, Valujskikh A, Fairchild RL, Baldwin WM, Acute and Chronic Rejection: Compartmentalization and Kinetics of Counterbalancing Signals in Cardiac Transplants. American Journal of Transplantation / Wiley Periodicals, Volume 15, Issue 2 (2015).
    2. Goparaju S, Kaul A, Dvorina N, Iida S, Keslar K, Fan R, de la Motte C, Valujskikh A, Fairchild R, Baldwin W, Low Molecular Weight Hyaluronan Increases MIG and MCP-1 Production in Cardiac Allografts, May 2015 American Journal of Transplantation, Special Issue: 2015 American Transplant Congress Abstracts, Volume 15, Issue S3, DOI: 10.1111/ajt.13359 / Wiley Periodicals.
  1. 1.      Poster Presentation, "Acute and Chronic Rejection: Compartmentalization and Kinetics of Counterbalancing Signals in Cardiac Transplants," at 2014 World Transplant Congress, July 26-31, Moscone West Convention Centre, San Francisco, California, USA (2014).

  2. 2.      Poster Presentation, "Compartmentalization of acute versus chronic rejection in cardiac allografts," at 2013- American Transplant Congress, May 18-22, Seattle, Washington, USA (2013).

  3. 3.      Poster Presentation, "Mechanisms underlying compartmentalization of acute versus chronic rejection in cardiac allografts," at 13th Annual Great lakes transplant Immunology forum, University of Wisconsin, October 10-11, Madison, Wisconsin, USA (2012).


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